The Drug Trial that went terribly wrong

The story of one of the most infamous medical emergencies in recent British history, when six healthy men took part in a drug trial that went terribly wrong.

On Monday 13 March 2006, eight healthy young men took part in a clinical trial of an experimental drug known as TGN1412. The drug was intended to treat leukaemia and had already been successfully tested on monkeys but never on humans.

 

Within an hour of receiving the drug, six of the volunteers were fighting for their lives: “It was all manic, everything was happening all at once, they were vomiting, they were screaming in pain, people fainting.”

 

 

The investigators tasked with discovering what went wrong: "This was treated as a crime scene. Something could have been tampered with, sabotaged, poisoned and that these folk might have been the victims of such foul play.”

 

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